• Ganoderma Fermentation Broth

    Ganoderma Submerged-Fermentation Broth/ Liquid

    Product Introduction:


    • 1.The only company can supply 100% Ganoderma fermentation broth in Taiwan.
    • 2.The Ganoderma fermentation broth abundant with biologically active polysaccharides,
      more than 5,000 mg/Kg, is produced by state-of-the-art automation fermentation technology
      using a strictly isolated rare Ganoderma strain.
    • 3.The product attributes are golden brown color, highly viscous, water soluble without
      sediment, and a little bit bitter, suitable for drink products.
    • 4.Also, the product quality is strictly controlled, without heavy metal and microbial
    • 5.Our long-term stability test has shown the product contains highly stable functional
      polysaccharides (no degradation)


Indicators of the product:

Polysaccharides ≧5000 mg/Kg
β-Glucan ≧4000 mg/L


β-D Glucan Report:

β-D Glucan is the key biologically active compound among the polysaccharides in the fermentation broth.
The more β-D Glucan, the better the health prospects.  

SCI Journal:


Isolating a cytoprotective compound from Ganoderma tsugae: effects

on induction of Nrf-2-related genes in endothelial cells.


Ganoderma tsugae is a medicinal fungus with several biological activities. It has long
been used as a folk remedy for the promotion of health and longevity in China and other
oriental countries. Here, a bioactive fraction of G. tsugae was progressively purified to be
enriched in the activity of cytoprotective enzymes. The highest bioactivity was detected in
the 20% EtOH-precipitated fraction, which was prepared from submerged fermentation
filtrate of G. tsugae. Following further purification by gel filtration chromatography and
acetone extraction, the most bioactive fraction, F5-2, was identified as a peptidoglycan-like
compound. Extracts of G. tsugae (F5-2) induced heme oxygenase-1 (HO-1) and thioredoxin
reductase-1 (TrxR1) expression in endothelial cells by increasing NF-E2-related factor-2(Nrf2)
nuclear translocation. Pretreatment with F5-2 increased intracellular glutathione (GSH) and
protected against H(2)O(2), suggesting that induction of these antioxidant enzymes is important
in protection against oxidative stress. Hence the bioactive peptidoglycan-like compound from G.

tsugae might protect endothelial cells.

Application :

a. The product is water soluble, and applicable for the product development of functional drink.
b. The product can be used as an additive, suitable for lacto vegetarian.